Radiation therapy alone or combined with chemotherapy in the treatment of esophageal cancer Journal Article
| Author: | Minsky, B. D. |
| Article Title: | Radiation therapy alone or combined with chemotherapy in the treatment of esophageal cancer |
| Abstract: | Radiation therapy has been used in the adjuvant setting or as a primary treatment modality for esophageal cancer. Although there are design flaws in all of the trials of adjuvant radiation therapy for esophageal cancer, there is no clear survival advantage when radiation therapy is delivered in the adjuvant setting (preoperatively or postoperatively). Phase II results of preoperative, combined modality therapy are encouraging; however, the approach remains investigational. When radiation therapy is used as a primary modality, the most favorable results are seen when it is combined with adequate doses of systemic chemotherapy. Phase III intergroup trials are in progress which are examining the effectiveness of higher doses of radiation therapy when combined with chemotherapy. |
| Keywords: | review; multimodality cancer therapy; radiation dose; combined modality therapy; radiotherapy dosage; radiotherapy; brachytherapy; esophagus tumor; esophageal neoplasms; humans; human |
| Journal Title: | Recent Results in Cancer Research |
| Volume: | 142 |
| ISSN: | 0080-0015 |
| Publisher: | Springer Verlag |
| Date Published: | 1996-01-01 |
| Start Page: | 217 |
| End Page: | 235 |
| Language: | English |
| PUBMED: | 8893344 |
| PROVIDER: | scopus |
| DOI: | 10.1007/978-3-642-80035-1_14 |
| DOI/URL: | |
| Notes: | Book Chapter in "New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors" (ISBN: 3-540-60498-7) -- Review -- Export Date: 22 November 2017 -- Source: Scopus |
