The protein machinery of vesicle budding and fusion Journal Article
| Author: | Rothman, J. E. |
| Article Title: | The protein machinery of vesicle budding and fusion |
| Abstract: | A general protein machinery that buds and fuses transport vesicles is harnessed to generate the complex web of intracellular transport pathways critical for such diverse processes as cell growth, endocytosis, hormone release, and neurotransmission. With this appreciation, the challenge of understanding the precise molecular mechanisms of these many facets of cell biology has been reduced to a series of problems in protein structure and chemistry. |
| Keywords: | review; proteins; animals; gtp-binding proteins; membrane proteins; intracellular transport; endoplasmic reticulum; hybrid protein; carrier proteins; protein structure; adenosine triphosphatase; guanosine triphosphate; biological transport; lipid bilayers; organelles; cell vacuole; vesicular transport proteins; intracellular membranes; guanosine 5'-o-(3-thiotriphosphate); coatomer protein; membrane fusion; golgi apparatus; coat protein; r-snare proteins; adp-ribosylation factors; priority journal; soluble n-ethylmaleimide-sensitive factor attachment proteins; golgi stack; budding and fusion mechanisms; soluble nsf attachment proteins, nsf protein, arf proteins, coat proteins, snare proteins |
| Journal Title: | Protein Science |
| Volume: | 5 |
| Issue: | 2 |
| ISSN: | 0961-8368 |
| Publisher: | Wiley Blackwell |
| Date Published: | 1996-02-01 |
| Start Page: | 185 |
| End Page: | 194 |
| Language: | English |
| PUBMED: | 8745395 |
| PROVIDER: | scopus |
| PMCID: | PMC2143331 |
| DOI: | 10.1002/pro.5560050201 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 22 November 2017 -- Source: Scopus |
