Thermotolerance and heat shock proteins: Possible involvement of Ku autoantigen in regulating Hsp70 expression Journal Article
| Authors: | Li, G. C.; Nussenzweig, A. |
| Article Title: | Thermotolerance and heat shock proteins: Possible involvement of Ku autoantigen in regulating Hsp70 expression |
| Abstract: | Here we characterize and compare the phenomenon of thermotolerance and permanent heat resistance in mammalian cells. The biochemical and molecular mechanisms underlying the induction of thermotolerance, and the role that heat shock proteins play in its development and decay are discussed. Finally, we describe a novel constitutive HSE-binding factor (CHBF/Ku) that appears to be involved in the regulation of the heat shock response. |
| Keywords: | dna binding protein; genetics; dna-binding proteins; review; metabolism; cell survival; dna repair; nuclear protein; luciferase; nuclear proteins; gene expression regulation; blotting, western; kinetics; western blotting; temperature; helicase; ku antigen; luciferases; blotting, northern; dna helicases; northern blotting; heat-shock proteins; antigens, nuclear; heat shock protein; cell nucleus antigen; heat; xrcc5 protein, human |
| Journal Title: | EXS |
| Volume: | 77 |
| ISSN: | 1023-294X |
| Publisher: | Birkhaeuser Science |
| Date Published: | 1996-01-01 |
| Start Page: | 425 |
| End Page: | 449 |
| Language: | English |
| PUBMED: | 8856989 |
| PROVIDER: | scopus |
| DOI: | 10.1007/978-3-0348-9088-5_29 |
| DOI/URL: | |
| Notes: | Chapter in "Stress-Inducible Cellular Responses" (ISBN: 978-3-0348-9901-7) Review -- Export Date: 22 November 2017 -- Source: Scopus |
