Atypical lipomatous tumor of the hand with transformation to dedifferentiated liposarcoma: A case report Journal Article


Authors: Ramirez, D. C.; Hwang, S.; Athanasian, E. A.; Wang, L.; Hameed, M.
Article Title: Atypical lipomatous tumor of the hand with transformation to dedifferentiated liposarcoma: A case report
Abstract: Atypical lipomatous tumor/well-differentiated liposarcoma is the most common sarcoma of soft tissue in adults. We describe the clinical, radiologic, and pathologic features of an atypical lipomatous tumor arising within the soft tissue of the left hand of a 68-year-old female that underwent transformation to dedifferentiated liposarcoma and eventually metastasized. At initial presentation, imaging demonstrated an extensively calcified fatty soft tissue mass with displacement of the digits. Following biopsy and staged debulking, the patient subsequently developed local recurrence, dedifferentiation, and widespread metastases to the lungs, pancreas, bone, and soft tissues. To our knowledge, this is the first case of a cytogenetically proven atypical lipomatous tumor of the hand that has undergone dedifferentiation with widespread metastases. © 2017, ISS.
Keywords: metastases; pet; ct; mri; liposarcoma; hand; dedifferentiated
Journal Title: Skeletal Radiology
Volume: 47
Issue: 5
ISSN: 0364-2348
Publisher: Springer  
Date Published: 2018-05-01
Start Page: 703
End Page: 709
Language: English
DOI: 10.1007/s00256-017-2832-1
PROVIDER: scopus
PUBMED: 29209735
PMCID: PMC6611678
DOI/URL:
Notes: Article -- Export Date: 1 May 2018 -- Source: Scopus
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MSK Authors
  1. Meera Hameed
    248 Hameed
  2. Sinchun Hwang
    86 Hwang
  3. Lu Wang
    147 Wang