Medication overuse in oncology: Current trends and future implications for patients and society Journal Article


Authors: Schleicher, S. M.; Bach, P. B.; Matsoukas, K.; Korenstein, D.
Article Title: Medication overuse in oncology: Current trends and future implications for patients and society
Abstract: The high cost of cancer care worldwide is largely attributable to rising drugs prices. Despite their high costs and potential toxic effects, anticancer treatments could be subject to overuse, which is defined as the provision of medical services that are more likely to harm than to benefit a patient. We found 30 studies documenting medication overuse in cancer, which included 16 examples of supportive medication overuse and 17 examples of antineoplastic medication overuse in oncology. Few specific agents have been assessed, and no studies investigated overuse of the most toxic or expensive medications currently used in cancer treatment. Although financial, psychological, or physical harms of medication overuse in cancer could be substantial, there is little published evidence addressing these harms, so their magnitude is unclear. Further research is needed to better quantify medication overuse, understand its implications, and help protect patients and the health-care system from overuse. © 2018 Elsevier Ltd
Journal Title: Lancet Oncology
Volume: 19
Issue: 4
ISSN: 1470-2045
Publisher: Elsevier Science, Inc.  
Date Published: 2018-04-01
Start Page: e200
End Page: e208
Language: English
DOI: 10.1016/s1470-2045(18)30099-8
PROVIDER: scopus
PUBMED: 29611528
PMCID: PMC6207078
DOI/URL:
Notes: Review -- Export Date: 1 May 2018 -- Source: Scopus
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  1. Peter Bach
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