Authors: | Pasternak, G.; Neilan, C. |
Editors: | Aminoff, M. J.; Daroff, R. B. |
Article/Chapter Title: | Neuropeptides; Overview |
Abstract: | For many years, it was assumed that neurotransmitters were small molecules. This changed in the 1970s with the discovery of a host of peptides within nervous tissue with their own receptors and neurotransmitter actions. These peptides are generated by enzymatic processing of longer peptides, often times yielding multiple active products from a single precursor peptide, and are typically inactivated by degradative enzymes. Uncovering this vast array of neuroactive peptides has expanded our understanding of the complexity of neurotransmission. © 2014 Elsevier Inc. All rights reserved. |
Keywords: | neuropeptide; enkephalin; dynorphin; neurotransmitter; peptide processing; peptidergic receptor |
Book Title: | Encyclopedia of the Neurological Sciences. 2nd ed |
ISBN: | 978-0-12-385157-4 |
Publisher: | Elsevier Inc. |
Publication Place: | London, United Kingdom |
Date Published: | 2014-01-01 |
Start Page: | 516 |
End Page: | 519 |
Language: | English |
DOI: | 10.1016/b978-0-12-385157-4.00043-9 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Book Chapter -- Export Date: 2 April 2018 -- Source: Scopus |