Rhabdomyosarcoma of the head and neck: A multimodal approach Journal Article
| Authors: | Casey, D. L.; Wolden, S. L. |
| Article Title: | Rhabdomyosarcoma of the head and neck: A multimodal approach |
| Abstract: | Head and neck rhabdomyosarcoma (HNRMS) is a uniquely challenging site to treat given the young patient age and critical anatomy of the head and neck region. We review the characteristics, management, and future directions in the treatment of HNRMS. Most patients who present with HNRMS have unresectable disease due to functional and/or cosmetic constraints. However, surgical resection and brachytherapy serve a critical role in select patients. The treatment paradigm for the majority of patients with HNRMS consists of definitive chemotherapy and radiation therapy. As the incidence of late toxicities increases with improved survival, modern efforts must focus on ways to decrease long-term morbidity. We recommend a multimodal approach emphasizing the preservation of form and function for the treatment of HNRMS. © Georg Thieme Verlag KG Stuttgart New York. |
| Keywords: | cancer survival; cancer surgery; overall survival; review; cancer combination chemotherapy; multimodality cancer therapy; cancer radiotherapy; cancer staging; outcome assessment; antineoplastic agent; radiotherapy; radiation injury; carcinogenesis; disease severity; head and neck neoplasms; brachytherapy; cataract; external beam radiotherapy; rhabdomyosarcoma; dry eye; tooth disease; intermediate risk patient; failure free survival; pediatric rhabdomyosarcoma; hypoplasia; human; priority journal; face deformity; head and neck rhabdomyosarcoma; facial hypoplasia |
| Journal Title: | Journal of Neurological Surgery. Part B: Skull Base |
| Volume: | 79 |
| Issue: | 1 |
| ISSN: | 2193-6331 |
| Publisher: | Thieme Publishing |
| Date Published: | 2018-02-01 |
| Start Page: | 58 |
| End Page: | 64 |
| Language: | English |
| DOI: | 10.1055/s-0037-1617450 |
| PROVIDER: | scopus |
| PMCID: | PMC5796820 |
| PUBMED: | 29404242 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 March 2018 -- Source: Scopus |
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