Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells—Power of nutraceuticals Journal Article


Authors: McCubrey, J. A.; Abrams, S. L.; Lertpiriyapong, K.; Cocco, L.; Ratti, S.; Martelli, A. M.; Candido, S.; Libra, M.; Murata, R. M.; Rosalen, P. L.; Lombardi, P.; Montalto, G.; Cervello, M.; Gizak, A.; Rakus, D.; Steelman, L. S.
Article Title: Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells—Power of nutraceuticals
Abstract: Over the past fifty years, society has become aware of the importance of a healthy diet in terms of human fitness and longevity. More recently, the concept of the beneficial effects of certain components of our diet and other compounds, that are consumed often by different cultures in various parts of the world, has become apparent. These “healthy” components of our diet are often referred to as nutraceuticals and they can prevent/suppress: aging, bacterial, fungal and viral infections, diabetes, inflammation, metabolic disorders and cardiovascular diseases and have other health-enhancing effects. Moreover, they are now often being investigated because of their anti-cancer properties/potentials. Understanding the effects of various natural products on cancer cells may enhance their usage as anti-proliferative agents which may be beneficial for many health problems. In this manuscript, we discuss and demonstrate how certain nutraceuticals may enhance other anti-cancer drugs to suppress proliferation of cancer cells. © 2017
Keywords: resveratrol; metformin; curcumin; berberine
Journal Title: Advances in Biological Regulation
Volume: 67
ISSN: 2212-4926
Publisher: Elsevier Inc.  
Date Published: 2018-01-01
Start Page: 190
End Page: 211
Language: English
DOI: 10.1016/j.jbior.2017.09.012
PROVIDER: scopus
PUBMED: 28988970
DOI/URL:
Notes: Article -- Export Date: 1 March 2018 -- Source: Scopus
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