The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy Book Section

  


Authors: Eccles, L. J.; O'Driscoll, C. A.; Carley, A. C.; Balciunaite, E.; Powell, S. N.
Editors: Madhusudan, S.; Wilson, D. M. 3rd
Article/Chapter Title: The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy
Keywords: proliferation; resolution; dna-damage response; strand-break repair; holliday junction; rad51 filament formation; embryonic cellular; fanconi-anemia subtype; poly(adp-ribose) polymerase inhibition; replication fork progression; brca1 tumor-suppressor; maintains genomic stability
Book Title: DNA Repair and Cancer: From Bench to Clinic
ISBN: 978-1-4665-7743-5
Publisher: CRC Press  
Publication Place: Boca Raton, FL
Date Published: 2013-01-01
Start Page: 470
End Page: 512
Language: English
ACCESSION: WOS:000353575000016
PROVIDER: wos
Notes: Book Chapter: 14 -- 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA -- Source: Wos