Proton therapy for head and neck cancers Journal Article
| Authors: | Blanchard, P.; Gunn, G. B.; Lin, A.; Foote, R. L.; Lee, N. Y.; Frank, S. J. |
| Article Title: | Proton therapy for head and neck cancers |
| Abstract: | Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has been used for decades in the treatment of skull-base tumors. In recent years the use of proton therapy has been extended to numerous other disease sites, including nasopharynx, oropharynx, nasal cavity and paranasal sinuses, periorbital tumors, skin, and salivary gland, or to reirradiation. The aim of this review is to present the physical properties and dosimetric benefit of proton therapy over advanced photon therapy; to summarize the clinical benefit described for each disease site; and to discuss issues of patient selection and cost-effectiveness. © 2017 |
| Keywords: | review; intensity modulated radiation therapy; advanced cancer; cancer risk; patient selection; follow up; diagnostic accuracy; prospective study; computer assisted tomography; skin cancer; practice guideline; cost effectiveness analysis; population research; disease severity; head and neck cancer; intensity-modulated radiotherapy; dosimetry; oropharynx cancer; radiation therapy; salivary gland cancer; nasopharynx cancer; radiation dose distribution; paranasal sinus cancer; proton therapy; re-irradiation; nose cavity cancer; orbit cancer; human; priority journal; intensity-modulated proton therapy; intensity modulated proton therapy |
| Journal Title: | Seminars in Radiation Oncology |
| Volume: | 28 |
| Issue: | 1 |
| ISSN: | 1053-4296 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2018-01-01 |
| Start Page: | 53 |
| End Page: | 63 |
| Language: | English |
| DOI: | 10.1016/j.semradonc.2017.08.004 |
| PROVIDER: | scopus |
| PUBMED: | 29173756 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 2 January 2018 -- Source: Scopus |
