To eat or not to eat - the metabolic flavor of ferroptosis Journal Article
| Authors: | Gao, M.; Jiang, X. |
| Article Title: | To eat or not to eat - the metabolic flavor of ferroptosis |
| Abstract: | Ferroptosis is a newly defined iron-dependent, non-apoptotic mode of cell death with necrotic morphology. Distinctive from other death mechanisms, ferroptosis requires cellular iron and lipid peroxides, and is dictated by specific cellular metabolic processes. Importantly, ferroptosis has been implicated in a plethora of human diseases. This paper reviews the recent advances and outstanding questions of the field by focusing on the role of cellular metabolism in ferroptosis. The relevance of ferroptosis to disease and therapy is also discussed. © 2017 Elsevier Ltd |
| Journal Title: | Current Opinion in Cell Biology |
| Volume: | 51 |
| ISSN: | 0955-0674 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2018-04-01 |
| Start Page: | 58 |
| End Page: | 64 |
| Language: | English |
| DOI: | 10.1016/j.ceb.2017.11.001 |
| PROVIDER: | scopus |
| PUBMED: | 29175614 |
| PMCID: | PMC5949249 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 2 January 2018 -- Source: Scopus |
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