Synthesis of the melanoma-associated ganglioside 9-O-acetyl GD3 through regioselective enzymatic acetylation of GD3 using subtilisin Journal Article
| Authors: | Takayama, S.; Livingston, P. O.; Wong, C. H. |
| Article Title: | Synthesis of the melanoma-associated ganglioside 9-O-acetyl GD3 through regioselective enzymatic acetylation of GD3 using subtilisin |
| Abstract: | The melanoma-associated disialoganglioside 9-O-acetyl GD3 has been synthesized for the first time through regioselective enzymatic acetylation of GD3 using subtilisin as the biocatalyst and vinyl acetate as the acetyl donor. |
| Keywords: | in vitro study; drug synthesis; melanoma antigen; catalysis; reaction analysis; acetylation; ganglioside; article; subtilisin |
| Journal Title: | Tetrahedron Letters |
| Volume: | 37 |
| Issue: | 52 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 1996-12-23 |
| Start Page: | 9271 |
| End Page: | 9274 |
| Language: | English |
| DOI: | 10.1016/s0040-4039(97)82939-5 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 22 November 2017 -- Source: Scopus |
