Benign and malignant phyllodes tumors: Mammographic and sonographic findings Journal Article


Authors: Liberman, L.; Bonaccio, E.; Hamele-Bena, D.; Abramson, A. F.; Cohen, M. A.; Dershaw, D. D.
Article Title: Benign and malignant phyllodes tumors: Mammographic and sonographic findings
Abstract: PURPOSE: To characterize imaging findings that suggest the benign or malignant histologic nature of phyllodes tumors. MATERIALS AND METHODS: Clinical and imaging findings were retrospectively reviewed in 46 women with 51 phyllodes tumors (32 benign, 19 malignant) identified at preoperative mammography. Thirty of these tumors were also evaluated with preoperative sonography. RESULTS: Mammography showed nonspiculated soft-tissue masses in 49 tumors. Four masses contained calcifications; three of these masses were benign. The tumors were 1-20 cm in diameter; tumors 3 cm or larger were statistically significantly more likely to be malignant (P < .004). Sonography showed solid, hypoechoic masses in 28 cases. At sonography, cystic areas were more often seen in malignant than in benign tumors, but the difference was not statistically significant. CONCLUSION: There is substantial overlap in the imaging characteristics of benign and malignant phyllodes tumors. A tumor diameter of 3 cm or greater appears to be associated with a higher likelihood of malignancy.
Keywords: adult; clinical article; aged; aged, 80 and over; middle aged; histopathology; preoperative evaluation; phyllodes tumor; cystosarcoma phylloides; echomammography; tumor volume; differential diagnosis; diagnostic imaging; breast neoplasms; retrospective study; mammography; breast tumor; tumor diagnosis; ultrasonography, mammary; breast calcification; humans; human; female; priority journal; article; breast neoplasms, diagnosis; breast neoplasms, us; breast neoplasms, radiography
Journal Title: Radiology
Volume: 198
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1996-01-01
Start Page: 121
End Page: 124
Language: English
PUBMED: 8539362
PROVIDER: scopus
DOI: 10.1148/radiology.198.1.8539362
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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  1. D David Dershaw
    223 Dershaw
  2. Laura Liberman
    176 Liberman
  3. Michael A Cohen
    14 Cohen