NMR solution structures of adducts derived from the binding of polycyclic aromatic diol epoxides to DNA Journal Article
| Authors: | Cosman, M.; Hingerty, B. E.; Amin, S.; Broyde, S.; Geacintov, N. E.; Patel, D. J. |
| Article Title: | NMR solution structures of adducts derived from the binding of polycyclic aromatic diol epoxides to DNA |
| Abstract: | Site-specifically modified oligonucleotides were derived from the reactions of stereoisomeric polycyclic aromatic diol epoxide metabolite model compounds with oligonucleotides of defined base composition and sequence. The NMR solution structures of ten different adducts studied so far are briefly described, and it is shown that stereochemical factors and the nature of the oligonucleotide context of the complementary strands, exert a powerful influence on the conformational features of these adducts. |
| Journal Title: | Polycyclic Aromatic Compounds |
| Volume: | 10 |
| Issue: | 1-4 |
| ISSN: | 1040-6638 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 1996-01-01 |
| Start Page: | 153 |
| End Page: | 160 |
| Language: | English |
| PROVIDER: | scopus |
| DOI: | 10.1080/10406639608034692 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 22 November 2017 -- Source: Scopus |
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