Pain in ambulatory AIDS patients. I: Pain characteristics and medical correlates Journal Article


Authors: Breitbart, W.; McDonald, M. V.; Rosenfeld, B.; Passik, S. D.; Hewitt, D.; Thaler, H.; Portenoy, R. K.
Article Title: Pain in ambulatory AIDS patients. I: Pain characteristics and medical correlates
Abstract: The characteristics and impact of pain were evaluated in a prospective cross-sectional survey of 438 ambulatory AIDS patients recruited from health care facilities in New York City. More than 60% of the patients reported 'frequent or persistent pain' during the 2 wks preceding the study. Patients with pain reported an average of 2.5 different pains. On the 0-10 numerical scale of the Brief Pain Inventory (BPI), mean pain intensity 'on average' was 5.4 (SD = 2.2; range = 0-10), and mean pain 'at its worst' was 7.4 (SD = 2.0; range = 1-10). The pain-related functional interference index (sum of the seven item BPI subscale) was 42.6 (SD = 17.2; range = 0-70). Demographic variables were not associated with the presence of pain, but the number of current HIV-related symptoms, treatment for HIV-related infections, and the absence of antiretroviral medications were significantly associated with the presence of pain. Female gender, non-Caucasian race, and number of HIV-related physical symptoms were significantly associated with pain intensity. Presence of pain and increasing pain intensity were significantly associated with greater impairment in functional ability (Karnofsky performance Status, BPI functional interference index) and physical symptom distress (Memorial Symptom Assessment Scale). Results demonstrate high levels of pain and pain-related functional impairment among patients with AIDS. The presence and intensity of pain are associated with more advanced HIV disease and pain intensity is also associated with demographic factors (gender, race).
Keywords: adolescent; adult; aged; middle aged; major clinical study; human immunodeficiency virus infection; prospective studies; reproducibility of results; demography; quality of life; pain; logistic models; age; symptom; disease severity; karnofsky performance status; predictive value of tests; ambulatory care; cross-sectional studies; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; pain measurement; gender; regression analysis; pain assessment; pain parameters; aids patients; humans; human; male; female; priority journal; article; medical correlates; pain characteristics
Journal Title: Pain
Volume: 68
Issue: 2-3
ISSN: 0304-3959
Publisher: Elsevier Science BV  
Date Published: 1996-12-01
Start Page: 315
End Page: 321
Language: English
DOI: 10.1016/s0304-3959(96)03215-0
PUBMED: 9121820
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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MSK Authors
  1. William S Breitbart
    504 Breitbart
  2. Steven D Passik
    122 Passik
  3. Howard T Thaler
    245 Thaler
  4. Russell K. Portenoy
    165 Portenoy