Unusual etiology of cough in a woman with asthma Journal Article


Authors: Sorhage, F.; Stover, D. E.; Mortazavi, A.
Article Title: Unusual etiology of cough in a woman with asthma
Abstract: A case of multiple symmetric lipomatosis (Madelung's disease) acquired through chronic use of corticosteroids is reported. Presumed symptoms of asthma, which consisted of a barking cough, were treated with escalating doses of steroids. We postulate that excessive use of steroids led to extensive mediastinal fatty infiltration with narrowing of the trachea and mainstem bronchi as noted both radiographically and bronchoscopically. When the steroids were tapered, there was marked improvement of the patient's symptoms and resolution of the upper airway intrathoracic obstruction. When patients with asthma are receiving optimal therapy and fail to improve, other causes for their symptoms should be considered.
Keywords: adult; case report; coughing; thorax radiography; asthma; corticosteroid; airway obstruction; lipomatosis; corticosteroid therapy; human; female; priority journal; article; upper airway obstruction; exogenous steroids; madehing's disease
Journal Title: Chest
Volume: 110
Issue: 3
ISSN: 0012-3692
Publisher: American College of Chest Physicians  
Date Published: 1996-09-01
Start Page: 852
End Page: 854
Language: English
DOI: 10.1378/chest.110.3.852
PUBMED: 8797442
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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