Laparoscopy: An important tool in the staging of malignant pleural mesothelioma Journal Article
| Authors: | Conlon, K. C.; Rusch, V. W.; Gillern, S. |
| Article Title: | Laparoscopy: An important tool in the staging of malignant pleural mesothelioma |
| Abstract: | Background: The current standard for the noninvasive staging of patients with malignant pleural mesothelioma is computed tomography (CT). However, CT often cannot determine whether a tumor is unresectable because of direct extension through the diaphragm to the peritoneal cavity. The aim of this prospective study was to determine whether laparoscopy detected transdiaphragmatic tumor extension when CT findings were equivocal. Methods: From June 1993 to July 1994, 12 of 36 patients considered for possible thoracotomy and surgical resection had equivocal CT findings of diaphragmatic invasion. All under-went laparoscopy using a multiport technique with diaphragmatic and peritoneal biopsies. Results: The mean operative time was 83 min. There were no perioperative complications. The median hospital stay was 1 day. Six patients had biopsy-proven transdiaphragmatic extension, or peritoneal studding of tumor. The other six patients subsequently underwent thoracotomy: three had a complete resection, and three had unresectable tumor due to chest wall (N = 2) or mediastinal (N = 1) invasion. In no case was transdiaphragmatic extension of a tumor seen. Conclusions: This preliminary experience demonstrates that laparoscopy is a safe and accurate method for detecting transdiaphragmatic tumor extension when CT fails to do so. Laparoscopy should be considered a standard part of prethoracotomy staging in this subset of patients. © 1996 The Society of Surgical Oncology, Inc. |
| Keywords: | aged; middle aged; comparative study; cancer staging; nuclear magnetic resonance imaging; methodology; magnetic resonance imaging; staging; neoplasm staging; laparoscopy; prospective study; prospective studies; computer assisted tomography; tomography, x-ray computed; pathology; biopsy; cancer invasion; length of stay; mesothelioma; pleura tumor; neoplasm invasiveness; diaphragm; pleural neoplasms; peritoneum; humans; human; male; article |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 3 |
| Issue: | 5 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 1996-07-01 |
| Start Page: | 489 |
| End Page: | 494 |
| Language: | English |
| PUBMED: | 8876892 |
| PROVIDER: | scopus |
| DOI: | 10.1007/BF02305768 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 22 November 2017 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work