Ureteral decompression in advanced nonurologic malignancies Journal Article


Authors: Donat, S.; Russo, P.
Article Title: Ureteral decompression in advanced nonurologic malignancies
Abstract: Background: The purpose of this study was to assess the morbidity and determine survival after ureteral decompression in patients with advanced nonurologic malignancies. Methods: Between June 1988 and June 1993 78 patients were referred to a single surgeon for ureteral decompression. Records were analyzed in relation to primary diagnosis, early and late complications, number of hospitalizations, and survival after decompression. Results: Seventy-two percent of patients initially underwent decompression endoscopically, and 28% required percutaneous nephrostomy placement at initial decompression. Complications occurred in 50% of patients and most commonly included infection (29%), stent obstruction and encrustation (28%), and gross hematuria (9%). The median survival for all patients after the first decompression procedure was 6.8 months (range 0.5-46.1), with an actuarial survival rate at 1 year of 55% and at 3 years of 30%. The eight patients with gastric/pancreatic cancer survived a median of just 1.4 months after decompression (range 0.77-11.8), with a 1 -year actuarial survival rate of 12.5% and 3-year actuarial survival of 0%, which was significantly worse when compared with all other groups taken together or individually (p < 0.03). Conclusions: Ureteral decompression procedures in patients with advanced cancer can be an important component of palliative care but are associated with significant morbidity (50%) in patients whose median survival is <7 months. The role of ureteral decompression in patients with advanced gastric and pancreatic cancer is limited. © 1996 The Society of Surgical Oncology, Inc.
Keywords: adult; aged; middle aged; survival rate; retrospective studies; mortality; pancreatic neoplasms; neoplasm; neoplasms; retrospective study; pancreas tumor; stent; cystoscopy; ureter; stomach neoplasms; stomach tumor; stents; ureter obstruction; decompression; obstruction; percutaneous nephrostomy; nephrostomy, percutaneous; ureteral obstruction; cancer; humans; human; male; female; article
Journal Title: Annals of Surgical Oncology
Volume: 3
Issue: 4
ISSN: 1068-9265
Publisher: Springer  
Date Published: 1996-07-01
Start Page: 393
End Page: 399
Language: English
PUBMED: 8790853
PROVIDER: scopus
DOI: 10.1007/BF02305670
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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  1. Paul Russo
    581 Russo
  2. Sherri M Donat
    174 Donat