Hepatic lobar atrophy: Association with ipsilateral portal vein obstruction Journal Article


Authors: Hann, L. E.; Getrajdman, G. I.; Brown, K. T.; Bach, A. M.; Teitcher, J. B.; Fong, Y.; Blumgart, L. H.
Article Title: Hepatic lobar atrophy: Association with ipsilateral portal vein obstruction
Abstract: OBJECTIVE. This study was performed to evaluate the association between hepatic lobar atrophy, bile duct obstruction, and portal vein obstruction. MATERIALS AND METHODS. Thirty cases of hepatic lobar atrophy identified on angiography with CT during arterial portography from August 1992 to March 1995 were retrospectively reviewed by two independent observers. Cases were evaluated for vascular patency and bile duct obstruction. Malignant diagnoses were present in 28 of 30 patients. RESULTS. Twenty-two patients (73% had atrophy in the left lobe and eight patients (27%) had right lobar atrophy. Portal vein obstruction wits unilateral and confined to the atrophic lobe in 26 patients (8%). In contrast, bile duct obstruction was bilateral in 23 patients (77%) and in only four patients (l3%) was it isolated to the atrophic lobe. The correlation between atrophy and portal vein obstruction was significantly, with 90% sensitivity, 97% specificity, and 96% positive predictive value (p < .00001). For the correlation between atrophy and biliary obstruction, the sensitivity of angiography with CT during arterial portography was 90%, specificity was 23% and positive predictive value was 54% (p = .17). CONCLUSION. Hepatic lobar atrophy usually occurs in the setting of combined biliary and portal vein obstruction. A significant correlation exists between hepatic lobar atrophy and ipsilateral portal vein obstruction.
Keywords: adult; clinical article; aged; middle aged; retrospective studies; sensitivity and specificity; neoplasms; disease association; computer assisted tomography; image analysis; atrophy; tomography, x-ray computed; diagnostic imaging; retrospective study; liver; contrast enhancement; predictive value of tests; bile duct carcinoma; bile duct obstruction; portal vein; angiography; intravenous drug administration; cholestasis; liver atrophy; diatrizoate; constriction, pathologic; portal vein obstruction; humans; human; male; female; priority journal; article; tolazoline
Journal Title: American Journal of Roentgenology
Volume: 167
Issue: 4
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 1996-10-01
Start Page: 1017
End Page: 1021
Language: English
PUBMED: 8819404
PROVIDER: scopus
DOI: 10.2214/ajr.167.4.8819404
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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MSK Authors
  1. Leslie H Blumgart
    352 Blumgart
  2. Ariadne Bach
    59 Bach
  3. Yuman Fong
    775 Fong
  4. Karen T Brown
    178 Brown
  5. Lucy E Hann
    69 Hann