Merkel cell carcinoma: CT findings in 12 patients Journal Article


Authors: Gollub, M. J.; Gruen, D. R.; Dershaw, D. D.
Article Title: Merkel cell carcinoma: CT findings in 12 patients
Abstract: OBJECTIVE. The purpose of this report is to determine CT imaging findings in patients with Merkel cell carcinoma. MATERIALS AND METHODS. Fifty-three CT scans in 12 patients with biopsy-proven Merkel cell carcinoma were retrospectively reviewed with regard to size, location, and attenuation of primary skin lesions and visceral and lymph node metastases. Findings that were present in 12 patients form the basis of this report. RESULTS. Primary skin lesions were manifested on CT scans in four patients as cutaneous nodules that were hyper- or isodense in relation to muscle. Sites of metastases included regional lymph nodes (n = 6), distant lymph nodes (n = 11), the liver (n = 3), and subcutaneous fat (n = 4). We also found metastases in the mediastinum, the peritoneum, the adrenal gland, and the lung. Usually nodal and subcutaneous metastases were slightly hyperdense. Subcutaneous linear stranding was associated with the lesions. CONCLUSION. CT is useful in the staging of Merkel cell carcinoma.
Keywords: clinical article; aged; cancer staging; lymph node metastasis; lymphatic metastasis; neoplasm staging; computer assisted tomography; skin defect; skin neoplasms; tomography, x-ray computed; diagnostic imaging; merkel cell tumor; carcinoma, merkel cell; clinical observation; humans; human; male; female; priority journal; article
Journal Title: American Journal of Roentgenology
Volume: 167
Issue: 3
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 1996-09-01
Start Page: 617
End Page: 620
Language: English
PUBMED: 8751663
PROVIDER: scopus
DOI: 10.2214/ajr.167.3.8751663
DOI/URL:
Notes: Article -- Export Date: 22 November 2017 -- Source: Scopus
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  1. D David Dershaw
    223 Dershaw
  2. Marc J Gollub
    209 Gollub