Study of nevi in children (SONIC): Baseline findings and predictors of nevus count Journal Article
| Authors: | Oliveria, S.; Satagopan, J. M.; Geller, A. C.; Dusza, S. W.; Weinstock, M. A.; Berwick, M.; Bishop, M.; Heneghan, M.; Halpern, A. C. |
| Article Title: | Study of nevi in children (SONIC): Baseline findings and predictors of nevus count |
| Abstract: | The authors report baseline findings and predictors of nevus count (log total nevi) at the completion of year 1 (2004) of the first known population-based, prospective study of nevi in a US cohort of children. Overall, 64% (n = 443/691) of grade 5 students and their parents in Framingham, Massachusetts, completed surveys and underwent digital photography. Total nevus count was associated with skin and hair color and tendency to burn, as measured by a sun sensitivity index. In multivariate analyses, male gender (rate ratio (RR) = 1.38, 95% confidence interval (CI): 1.22, 1.55; P < 0.0001), spending 5-6 weekly hours outdoors between 10 AM and 4 PM (RR = 1.13, 95% CI: 1.00, 1.28; P = 0.051), getting a painful sunburn once (RR = 1.24, 95% CI: 0.98, 1.57; P = 0.073) and at least twice (RR = 1.34, 95% CI: 0.99, 1.82; P = 0.061), and wearing a shirt at the beach or pool rarely (RR = 1.29, 95% CI: 1.08, 1.54; P = 0.005), sometimes (RR = 1.26, 95% CI: 1.01, 1.57; P = 0.041), and often and always (RR = 1.32, 95% CI: 1.13, 1.54; P = 0.001) were associated with increased number of nevi. Identifying factors that predict the development of nevi will improve primary prevention efforts during early life. © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. |
| Keywords: | adolescent; adult; child; major clinical study; united states; prospective study; prospective studies; melanoma; cohort studies; nevus; skin neoplasms; cohort analysis; odds ratio; risk factors; mass screening; risk assessment; questionnaires; hair color; confidence interval; confidence intervals; skin; longitudinal studies; nevus, pigmented; population; skin examination; public health; multivariate analysis; gender; ultraviolet rays; photography; analysis of variance; environmental exposure; primary prevention; north america; sunburn; parents; child health; student; parent; photometry; population based case control study; school; seashore; sun; massachusetts; framingham |
| Journal Title: | American Journal of Epidemiology |
| Volume: | 169 |
| Issue: | 1 |
| ISSN: | 0002-9262 |
| Publisher: | Oxford University Press |
| Date Published: | 2009-01-01 |
| Start Page: | 41 |
| End Page: | 53 |
| Language: | English |
| DOI: | 10.1093/aje/kwn289 |
| PUBMED: | 19001133 |
| PROVIDER: | scopus |
| PMCID: | PMC2720704 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 30 November 2010" - "CODEN: AJEPA" - "Source: Scopus" |
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