Authors: | Codega, P.; Mellinghoff, I. K. |
Article Title: | Dissecting glioma invasiveness in a 3D-organotypic model |
Abstract: | Diffuse brain infiltration by tumor cells is a hallmark of glioma. Molecular mechanisms of brain invasion are poorly understood due to the difficulty to model this process in culture. A new study published in Cell Reports developed a three-dimensional organotypic model and identified interferon regulatory factor 3 (IRF3) as repressor of glioma invasion. © 2017 Elsevier Ltd |
Journal Title: | Trends in Molecular Medicine |
Volume: | 23 |
Issue: | 9 |
ISSN: | 1471-4914 |
Publisher: | Elsevier Inc. |
Date Published: | 2017-09-01 |
Start Page: | 776 |
End Page: | 777 |
Language: | English |
DOI: | 10.1016/j.molmed.2017.07.009 |
PROVIDER: | scopus |
PMCID: | PMC5588876 |
PUBMED: | 28781061 |
DOI/URL: | |
Notes: | Short Survey -- Export Date: 2 October 2017 -- Source: Scopus |