Contamination artifact that mimics in-situ carcinoma on contrast-enhanced digital mammography Journal Article

   


Authors: Gluskin, J.; Click, M.; Fleischman, R.; Dromain, C.; Morris, E. A.; Jochelson, M. S.
Article Title: Contamination artifact that mimics in-situ carcinoma on contrast-enhanced digital mammography
Abstract: Purpose Contrast-enhanced digital mammography (CEDM) is an advanced breast imaging technique using iodinated intravenous contrast to detect breast cancer. This article describes imaging features of a skin contamination artifact on CEDM that mimics in-situ carcinoma in a case series. Materials and methods Five patients were identified whose CEDM images demonstrated apparent calcifications and non-mass enhancement suspicious for in-situ carcinoma, with no subsequent evidence of disease. Retrospective image analysis was performed on the unprocessed image data, processed images, and imaging parameters. Dual-energy mammographic technique was performed on two breast phantoms with varying degrees of topical contrast contamination. Results Temporal analysis confirmed the suspicious finding was neither an abnormality of the compression paddle nor the receptor. Comparison of LE and HE images demonstrated the suspicious finding attenuated near the K-edge of iodine, suggesting contrast contamination. Iodinated contrast applied to the surface of breast phantoms replicated the artifact, with a pattern of apparent enhancement similar to the appearance of in-situ carcinoma. Conclusion Skin contamination with iodinated contrast can result in an artifact on post-contrast digital mammography that mimics the appearance of in-situ carcinoma. © 2017
Keywords: contrast enhanced digital mammography; contamination artifact; iodinated contrast
Journal Title: European Journal of Radiology
Volume: 95
ISSN: 0720-048X
Publisher: Elsevier B.V  
Date Published: 2017-10-01
Start Page: 147
End Page: 154
Language: English
DOI: 10.1016/j.ejrad.2017.08.002
PROVIDER: scopus
PMCID: PMC7590507
PUBMED: 28987661
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027587107&doi=10.1016%2fj.ejrad.2017.08.002&partnerID=40&md5=00f6024fea1e6f5f807efade67787374
Notes: Article -- Export Date: 5 September 2017 -- Source: Scopus
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MSK Authors
  1. Elizabeth A Morris
    341 Morris
  2. Maxine Jochelson
    135 Jochelson
  3. Richard Fleischman
    10 Fleischman
  4. Jill Stacey Gluskin
    27 Gluskin
  5. Michael E Click
    1 Click
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