Re-irradiation therapy for locally recurrent head and neck cancer: A national survey of practice patterns Journal Article


Authors: Rwigema, J. C. M.; Choi, J.; Lee, N. Y.; Heron, D. E.; Chen, A. M.
Article Title: Re-irradiation therapy for locally recurrent head and neck cancer: A national survey of practice patterns
Abstract: Using a customized survey consisting of two de-identified clinical scenarios with a total of 86 questions, we showed that substantial variability exists regarding recommendations for therapy of recurrent head and neck cancer. For inoperable gross recurrence arising in a previously irradiated field, recommendations were re-irradiation with curative intent (73%), re-irradiation with palliative intent (4%), chemotherapy alone (5%), and referral to tertiary center (18%). After salvage surgery, only 33% recommended adjuvant re-irradiation, with the remainder preferring observation (46%), chemotherapy alone (10%), and referral to tertiary center (11%). Significant differences were observed with respect to dose, fractionation, technique, and systemic therapy recommendations. © 2017 Taylor & Francis Group, LLC.
Keywords: salvage therapy; head and neck cancer; recurrent; re-irradiation; practice patterns
Journal Title: Cancer Investigation
Volume: 35
Issue: 6
ISSN: 0735-7907
Publisher: Informa Healthcare  
Date Published: 2017-01-01
Start Page: 393
End Page: 402
Language: English
DOI: 10.1080/07357907.2017.1310222
PROVIDER: scopus
PUBMED: 28437131
DOI/URL:
Notes: Article -- Export Date: 1 September 2017 -- Source: Scopus
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  1. Nancy Y. Lee
    871 Lee