Cancer treatment as an accelerated aging process: Assessment, biomarkers, and interventions Journal Article


Authors: Hurria, A.; Jones, L.; Muss, H. B.
Article Title: Cancer treatment as an accelerated aging process: Assessment, biomarkers, and interventions
Abstract: An accumulating body of evidence supports the hypothesis that cancer and/or cancer treatment is associated with accelerated aging. The majority of these data come from the pediatric literature; however, a smaller yet growing body of literature points toward similar findings in the geriatric population. This is a key survivorship issue the growing number of older adults with cancer face, along with the short- and long-term impact of cancer therapy on the aging process. This article will review clinical and biologic markers of aging in older adults with cancer, use cardiovascular disease as a model of accelerated aging, and discuss potential interventions to decrease the risk.
Keywords: aged; aged, 80 and over; pathophysiology; neoplasms; biomarkers; biological marker; pathology; survivor; survivors; cardiovascular disease; cardiovascular diseases; aging; geriatric assessment; drug effects; very elderly; humans; human; chemically induced
Journal Title: American Society of Clinical Oncology Educational Book
Volume: 36
ISSN: 1548-8756
Publisher: American Society of Clinical Oncology  
Date Published: 2016-05-01
Start Page: e516
End Page: e522
Language: English
DOI: 10.14694/EDBK_156160
PUBMED: 27249761
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 2 August 2017 -- Source: Scopus
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  1. Lee Winston Jones
    177 Jones