Cancer treatment as an accelerated aging process: Assessment, biomarkers, and interventions Journal Article
| Authors: | Hurria, A.; Jones, L.; Muss, H. B. |
| Article Title: | Cancer treatment as an accelerated aging process: Assessment, biomarkers, and interventions |
| Abstract: | An accumulating body of evidence supports the hypothesis that cancer and/or cancer treatment is associated with accelerated aging. The majority of these data come from the pediatric literature; however, a smaller yet growing body of literature points toward similar findings in the geriatric population. This is a key survivorship issue the growing number of older adults with cancer face, along with the short- and long-term impact of cancer therapy on the aging process. This article will review clinical and biologic markers of aging in older adults with cancer, use cardiovascular disease as a model of accelerated aging, and discuss potential interventions to decrease the risk. |
| Keywords: | aged; aged, 80 and over; pathophysiology; neoplasms; biomarkers; biological marker; pathology; survivor; survivors; cardiovascular disease; cardiovascular diseases; aging; geriatric assessment; drug effects; very elderly; humans; human; chemically induced |
| Journal Title: | American Society of Clinical Oncology Educational Book |
| Volume: | 36 |
| ISSN: | 1548-8756 |
| Publisher: | American Society of Clinical Oncology |
| Date Published: | 2016-05-01 |
| Start Page: | e516 |
| End Page: | e522 |
| Language: | English |
| DOI: | 10.14694/EDBK_156160 |
| PUBMED: | 27249761 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 2 August 2017 -- Source: Scopus |
