The antiandrogen withdrawal syndrome in relapsed prostate cancer Conference Paper


Authors: Scher, H. I.; Kolvenbag, G. J. C. M.
Title: The antiandrogen withdrawal syndrome in relapsed prostate cancer
Conference Title: New Avenues and Perspectives in the Management of Advanced Prostate Cancer
Abstract: Evolving data suggest that palliation of relapsed prostate cancer can be achieved by the selective discontinuation of agents that act via steroid hormone receptors. Clinical benefit has been observed following the withdrawal of flutamide (Eulexin®, Schering-Plough International), bicalutamide (Casodex®, Zeneca Ltd), oestrogens, progestational agents and retinoids. For patients with progression of disease while receiving these drugs, a period of observation after withdrawal should be considered before further therapy is initiated.
Keywords: cancer recurrence; conference paper; cancer palliative therapy; palliative care; estrogen; withdrawal syndrome; prostate cancer; prostate-specific antigen; prostatic neoplasms; disease progression; androgen antagonists; antiandrogen; bicalutamide; flutamide; antineoplastic agents, hormonal; steroid receptor; retinoid; gestagen; combined androgen blockade; antiandrogen therapy; antiandrogen withdrawal syndrome; humans; human; male; priority journal; bicalutamide (casodex®); flutamide (eulexin®)
Journal Title European Urology
Volume: 31
Issue: Suppl. 2
Conference Dates: 1996 Sep 1
Conference Location: Paris, France
ISBN: 0302-2838
Publisher: Elsevier Science, Inc.  
Date Published: 1997-02-01
Start Page: 3
End Page: 7; discussion 24-27
Language: English
PUBMED: 9074903
PROVIDER: scopus
DOI/URL:
Notes: Conference Paper -- Export Date: 17 March 2017 -- Source: Scopus
Citation Impact
MSK Authors
  1. Howard Scher
    1130 Scher