The role of multimodality therapy in locoregional non-small cell lung cancer Journal Article
| Authors: | Martini, N.; Kris, M. G.; Ginsberg, R. J. |
| Article Title: | The role of multimodality therapy in locoregional non-small cell lung cancer |
| Abstract: | Surgical treatment is offered to all patients with stage I or II disease and to specific groups of patients with stage III or IV disease. Cisplatin based on regimens of induction chemotherapy or chemoradiotherapy have proven to be valuable in stage IIIA (N2) disease. We now recommend induction therapy on an investigational basis to most patients with stage I or II tumors and to all those with stage IIIA tumors, when the 5 year survival is anticipated to be less than 50% with conventional therapy. Many new chemotherapy agents effective in advanced stage lung cancer are currently integrated into this mutlimodality approach in hopes of further improvement in tumor control and survival. |
| Keywords: | cancer survival; survival rate; review; cigarette smoking; cisplatin; doxorubicin; multimodality cancer therapy; antineoplastic agents; paclitaxel; postoperative care; chemotherapy, adjuvant; combined modality therapy; radiotherapy, adjuvant; cancer staging; lymph node metastasis; lymphatic metastasis; neoplasm staging; bcg vaccine; carboplatin; computer assisted tomography; neoplasm recurrence, local; lung lobectomy; lung non small cell cancer; lung resection; antineoplastic combined chemotherapy protocols; carcinoma, non-small-cell lung; lung neoplasms; pneumonectomy; cyclophosphamide; chlormethine; brachytherapy; vindesine; thorax radiography; neoplasm invasiveness; preoperative treatment; isotretinoin; mitomycin; levamisole; pancoast tumor; humans; prognosis; human; male; female |
| Journal Title: | Surgical Oncology Clinics of North America |
| Volume: | 6 |
| Issue: | 4 |
| ISSN: | 1055-3207 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1997-10-01 |
| Start Page: | 769 |
| End Page: | 791 |
| Language: | English |
| PUBMED: | 9309093 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 17 March 2017 -- Source: Scopus |
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