Pleurectomy/decortication in the setting of multimodality treatment for diffuse malignant pleural mesothelioma Journal Article


Author: Rusch, V. W.
Article Title: Pleurectomy/decortication in the setting of multimodality treatment for diffuse malignant pleural mesothelioma
Abstract: Pleurectomy/decortication is a frequently performed operation for patients with diffuse malignant pleural mesothelioma (DMPM). It has a low surgical mortality rate (less than 5%), but is associated with a significant risk of local recurrence. To date, intensive adjuvant radiation or chemotherapy has not diminished that risk. Despite these disappointing results, pleurectomy/decortication may still be the best treatment option for some patients, particularly those with early stage disease whose medical condition precludes pneumonectomy. The role of pleurectomy/decortication in conjunction with newer treatment strategies such as neoadjuvant therapy or gene therapy warrants investigation.
Keywords: treatment outcome; retrospective studies; review; multimodality cancer therapy; antineoplastic agents; combined modality therapy; antineoplastic agent; dissection; retrospective study; mesothelioma; pleura tumor; diaphragm; pleural neoplasms; humans; human
Journal Title: Seminars in Thoracic and Cardiovascular Surgery
Volume: 9
Issue: 4
ISSN: 1043-0679
Publisher: Elsevier Inc.  
Date Published: 1997-10-01
Start Page: 367
End Page: 372
Language: English
PUBMED: 9352954
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 17 March 2017 -- Source: Scopus
Citation Impact
MSK Authors
  1. Valerie W Rusch
    864 Rusch