Treatment of malignant pleural mesothelioma Journal Article
| Author: | Rusch, V. W. |
| Article Title: | Treatment of malignant pleural mesothelioma |
| Abstract: | The management of malignant pleural mesothelioma (MPM) is controversial and is often viewed nihilistically because of the relative inefficacy of standard therapeutic modalities in this disease. However, a new international staging system, the development of novel treatment strategies, and ongoing prospective clinical trials provide hope of improving the currently poor survival rates of MPM. Surgical resection with adjuvant radiation and/or chemotherapy has modestly improved local control and survival. New treatments including photodynamic therapy, immunotherapy, and gene therapy are being evaluated. Future treatment regimens will need to be multimodal in approach and take into consideration tumor stage and histology. |
| Keywords: | treatment outcome; unclassified drug; review; cisplatin; doxorubicin; fluorouracil; cancer risk; paclitaxel; treatment; methotrexate; cancer staging; staging; antineoplastic agent; bcg vaccine; carboplatin; interleukin 2; cyclophosphamide; risk factor; ifosfamide; immunotherapy; gamma interferon; folinic acid; mitoxantrone; gene therapy; pleura mesothelioma; mesothelioma; epirubicin; vindesine; amsacrine; alpha2a interferon; mitomycin; photodynamic therapy; occupational exposure; diaziquone; trimetrexate; pirarubicin; edatrexate; prognosis; human; priority journal; detorubicin; 10 propargyl 5,8 dideazafolic acid; 5,6 dihydroazacitidine; acivcin |
| Journal Title: | Seminars in Respiratory and Critical Care Medicine |
| Volume: | 18 |
| Issue: | 4 |
| ISSN: | 1069-3424 |
| Publisher: | Thieme Publishing |
| Date Published: | 1997-07-01 |
| Start Page: | 363 |
| End Page: | 373 |
| Language: | English |
| PROVIDER: | scopus |
| DOI: | 10.1055/s-2007-1009351 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 17 March 2017 -- Source: Scopus |
