Adjuvant treatment of colorectal cancer Journal Article


Authors: Saltz, L. B.; Kelsen, D. P.
Article Title: Adjuvant treatment of colorectal cancer
Abstract: The adjuvant therapy of colorectal cancer has seen many important advances in recent years. Chemotherapy improves long-term disease-free survival rates in high-risk patients with resected colon cancer. Combined modality therapy, using surgery, radiation therapy, and chemotherapy, improves both local control and survival in patients with stage II and III rectal cancer. We examine in detail the data on which current recommendations for adjuvant treatments are based. We also review some of the more promising experimental approaches currently under investigation.
Keywords: cancer survival; treatment outcome; survival rate; review; multimodality cancer therapy; cancer adjuvant therapy; chemotherapy, adjuvant; combined modality therapy; radiotherapy, adjuvant; chemotherapy; cancer staging; antineoplastic agent; neoplasm staging; colorectal cancer; high risk patient; colorectal neoplasms; immunotherapy; randomized controlled trials; radiation therapy; adjuvant; humans; human; priority journal
Journal Title: Annual Review of Medicine
Volume: 48
ISSN: 0066-4219
Publisher: Annual Reviews  
Date Published: 1997-01-01
Start Page: 191
End Page: 202
Language: English
DOI: 10.1146/annurev.med.48.1.191
PUBMED: 9046955
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Leonard B Saltz
    790 Saltz
  2. David P Kelsen
    537 Kelsen