Authors: | Benson, A. B. 3rd; Venook, A. P.; Cederquist, L.; Chan, E.; Chen, Y. J.; Cooper, H. S.; Deming, D.; Engstrom, P. F.; Enzinger, P. C.; Fichera, A.; Grem, J. L.; Grothey, A.; Hochster, H. S.; Hoffe, S.; Hunt, S.; Kamel, A.; Kirilcuk, N.; Krishnamurthi, S.; Messersmith, W. A.; Mulcahy, M. F.; Murphy, J. D.; Nurkin, S.; Saltz, L.; Sharma, S.; Shibata, D.; Skibber, J. M.; Sofocleous, C. T.; Stoffel, E. M.; Stotsky-Himelfarb, E.; Willett, C. G.; Wu, C. S.; Gregory, K. M.; Freedman-Cass, D. |
Article Title: | Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology |
Abstract: | This portion of the NCCN Guidelines for Colon Cancer focuses on the use of systemic therapy in metastatic disease. Considerations for treatment selection among 32 different monotherapies and combination regimens in up to 7 lines of therapy have included treatment history, extent of disease, goals of treatment, the efficacy and toxicity profiles of the regimens, KRAS/NRAS mutational status, and patient comorbidities and preferences. Location of the primary tumor, the BRAF mutation status, and tumor microsatellite stability should also be considered in treatment decisions. © 2017 National Comprehensive Cancer Network, Inc. All rights reserved. |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 15 |
Issue: | 3 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2017-03-01 |
Start Page: | 370 |
End Page: | 398 |
Language: | English |
PROVIDER: | scopus |
PUBMED: | 28275037 |
DOI: | 10.6004/jnccn.2017.0036 |
DOI/URL: | |
Notes: | Review -- Export Date: 2 May 2017 -- Source: Scopus |