Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation Journal Article


Authors: Snyder, H. M.; Ahles, T.; Calderwood, S.; Carrillo, M. C.; Chen, H.; Chang, C. C. H.; Craft, S.; De Jager, P.; Driver, J. A.; Fillit, H.; Knopman, D.; Lotze, M.; Tierney, M. C.; Petanceska, S.; Saykin, A.; Seshadri, S.; Shineman, D.; Ganguli, M.
Article Title: Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation
Abstract: Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer's disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened a one-day workshop to delve into this discussion. Workshop participants outlined research focus areas, potential collaborations, and partnerships for future action. © 2016 the Alzheimer's Association
Keywords: genetics; oncology; epidemiology; alzheimer's disease; cancer; biological mechanisms; repurpose therapy
Journal Title: Alzheimer's & Dementia
Volume: 13
Issue: 3
ISSN: 1552-5260
Publisher: Alzheimer's Association  
Date Published: 2017-03-01
Start Page: 267
End Page: 273
Language: English
DOI: 10.1016/j.jalz.2016.11.002
PROVIDER: scopus
PUBMED: 27998721
PMCID: PMC5548424
DOI/URL:
Notes: Review -- Export Date: 4 April 2017 -- Source: Scopus
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  1. Tim A Ahles
    182 Ahles