Authors: | Balog, A.; Bertinato, P.; Su, D. S.; Meng, D.; Sorensen, E.; Danishefsky, S. J.; Zheng, Y. H.; Chou, T. C.; He, L.; Horwitz, S. B. |
Article Title: | Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties |
Abstract: | The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction. |
Keywords: | controlled study; unclassified drug; human cell; paclitaxel; antineoplastic agent; antineoplastic activity; drug screening; drug synthesis; leukemia cell; reaction analysis; epothilone a; epothilone derivative; epoxidation; human; article |
Journal Title: | Tetrahedron Letters |
Volume: | 38 |
Issue: | 26 |
ISSN: | 0040-4039 |
Publisher: | Pergamon-Elsevier Science Ltd |
Date Published: | 1997-06-30 |
Start Page: | 4529 |
End Page: | 4532 |
Language: | English |
DOI: | 10.1016/s0040-4039(97)00931-3 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 17 March 2017 -- Source: Scopus |