Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties Journal Article


Authors: Balog, A.; Bertinato, P.; Su, D. S.; Meng, D.; Sorensen, E.; Danishefsky, S. J.; Zheng, Y. H.; Chou, T. C.; He, L.; Horwitz, S. B.
Article Title: Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties
Abstract: The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.
Keywords: controlled study; unclassified drug; human cell; paclitaxel; antineoplastic agent; antineoplastic activity; drug screening; drug synthesis; leukemia cell; reaction analysis; epothilone a; epothilone derivative; epoxidation; human; article
Journal Title: Tetrahedron Letters
Volume: 38
Issue: 26
ISSN: 0040-4039
Publisher: Pergamon-Elsevier Science Ltd  
Date Published: 1997-06-30
Start Page: 4529
End Page: 4532
Language: English
DOI: 10.1016/s0040-4039(97)00931-3
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Aaron Balog
    14 Balog
  2. Ting-Chao Chou
    319 Chou
  3. Dongfang   Meng
    17 Meng
  4. Dai-Shi   Su
    12 Su