Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy Journal Article


Authors: Abu-Rustum, N. R.; Curtin, J. P.; Burt, M.; Jones, W. B.
Article Title: Regression of uterine low-grade smooth-muscle tumors metastatic to the lung after oophorectomy
Abstract: Background: Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smooth-muscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease. Cases: Two women with histologically confirmed uterine low-grade smooth- muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy. Conclusion: Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy.
Keywords: adult; human tissue; disease-free survival; case report; follow-up studies; hysterectomy; salpingooophorectomy; computer assisted tomography; diagnosis, differential; lung neoplasms; ovariectomy; lung metastasis; remission induction; leiomyosarcoma; lung biopsy; uterine neoplasms; uterus myoma; muscle tumor; lung nodule; uterus tumor; myometrium; leiomyoma; humans; human; female; priority journal; article
Journal Title: Obstetrics and Gynecology
Volume: 89
Issue: 5 Pt. 2
ISSN: 0029-7844
Publisher: Lippincott Williams & Wilkins  
Date Published: 1997-05-01
Start Page: 850
End Page: 852
Language: English
DOI: 10.1016/s0029-7844(97)00033-1
PUBMED: 9166348
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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  1. John P Curtin
    112 Curtin
  2. Walter   Jones
    95 Jones
  3. Michael E. Burt
    187 Burt