Fast and localized event-related optical signals (EROS) in the human occipital cortex: Comparisons with the visual evoked potential and fMRI Journal Article
| Authors: | Gratton, G.; Fabiani, M.; Corballis, P. M.; Hood, D. C.; Goodman-Wood, M. R.; Hirsch, J.; Kim, K.; Friedman, D.; Gratton, E. |
| Article Title: | Fast and localized event-related optical signals (EROS) in the human occipital cortex: Comparisons with the visual evoked potential and fMRI |
| Abstract: | Localized evoked activity of the human cortex produces fast changes in optical properties that can be detected noninvasively (event-related optical signal, or EROS). In the present study a fast EROS response (latency ≃ 100 ms) elicited in the occipital cortex by visual stimuli showed spatial congruence with fMRI signals and temporal correspondence with VEPs, thus combining subcentimeter spatial localization with subsecond temporal resolution. fMRI signals were recorded from striate and extrastriate cortex. Both areas showed EROS peaks, but at different latencies after stimulation (100 and 200-300 ms, respectively). These results suggest that EROS manifests localized neuronal activity associated with information processing. The temporal resolution and spatial localization of this signal make it a promising tool for studying the time course of activity in localized brain areas and for bridging the gap between electrical and hemodynamic imaging methods. |
| Keywords: | adult; case report; nuclear magnetic resonance imaging; magnetic resonance imaging; image analysis; information processing; time factors; intermethod comparison; fmri; brain mapping; photic stimulation; brain function; optics; photon; evoked potentials, visual; evoked visual response; occipital lobe; spatial discrimination; humans; human; male; female; priority journal; article; ocular physiology; occipital cortex; event-related optical signal (eros); functional brain mapping; noninvasive optical imaging; photon migration in tissues; veps |
| Journal Title: | NeuroImage |
| Volume: | 6 |
| Issue: | 3 |
| ISSN: | 1053-8119 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 1997-10-01 |
| Start Page: | 168 |
| End Page: | 180 |
| Language: | English |
| DOI: | 10.1006/nimg.1997.0298 |
| PUBMED: | 9344821 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 17 March 2017 -- Source: Scopus |
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