Ninety-six five-year survivors after liver resection for metastatic colorectal cancer Journal Article
| Authors: | D'Angelica, M.; Brennan, M. F.; Fortner, J. G.; Cohen, A. M.; Blumgart, L. H.; Fong, Y. |
| Article Title: | Ninety-six five-year survivors after liver resection for metastatic colorectal cancer |
| Abstract: | Background: Studies have consistently confirmed the benefit of liver resection for metastatic colorectal cancer. Few reports, however, have a long enough followup or sufficient 5-year survivors to study the clinical course of patients beyond 5 years. Study Design: From July 1985 through December 1991, 456 patients underwent liver resection for colorectal metastases. Ninety-six actual 5-year survivors (21%) were identified and their clinical course retrospectively reviewed. Results: Five-year survivors (n = 96) were more likely to have a Duke's B primary colorectal carcinoma, fewer than four metastatic lesions, unilobar disease, and a negative histologic margin when compared with patients not surviving 5 years (n = 298). Forty-four (46%) of the 96 five-year survivors had a recurrence after hepatectomy. Of these 44, 19 (43%) were rendered disease free after further treatment. Overall, 71 of the 96 five-year survivors were free of disease at last followup. The actuarial 10-year survival of this group was 78%. Conclusions: Patients that are disease free 5 years after liver resection are likely to have been cured by liver resection. Patients should be aggressively followed for recurrence because of the potential for further treatment and longterm survival. © 1997 by the American College of Surgeons. |
| Keywords: | survival; adult; aged; disease-free survival; middle aged; survival analysis; mortality; liver neoplasms; comparative study; disease free survival; methodology; metastasis; statistics; pathology; survivor; survivors; colorectal neoplasms; colorectal tumor; liver tumor; liver resection; chi-square distribution; hepatectomy; multivariate analysis; chi square distribution; humans; prognosis; human; male; female; article |
| Journal Title: | Journal of the American College of Surgeons |
| Volume: | 185 |
| Issue: | 6 |
| ISSN: | 1072-7515 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 1997-12-01 |
| Start Page: | 554 |
| End Page: | 559 |
| Language: | English |
| PUBMED: | 9404879 |
| PROVIDER: | scopus |
| DOI: | 10.1016/S1072-7515(97)00103-8 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 17 March 2017 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work