Stress and genetic testing for disease risk Journal Article
| Authors: | Baum, A.; Friedman, A. L.; Zakowski, S. G. |
| Article Title: | Stress and genetic testing for disease risk |
| Abstract: | Healthy people who believe they are at risk for a life-threatening disease appear to carry a substantial stress burden because of threat of disease and uncertainty of risk. Testing for risk factors may be helpful by reducing this uncertainty, but diseases with multiple causes, like breast cancer, appear to be determined by genetic factors and by age, reproductive behavior, exposure to environmental toxins, or unknown antecedents. For diseases caused by inherited genetic defects, testing brings different benefits and stressors. A model is proposed that predicts long-term distress when risk analysis suggests a very high risk, when uncertainty is not reduced, when results of testing are at odds with preventive actions already taken, and when people who receive a positive, risk-increasing result lack strong social support, coping skills, other psychosocial resources, or all of these. |
| Keywords: | treatment outcome; genetics; genetic predisposition to disease; breast neoplasms; risk assessment; adaptive behavior; psychological aspect; adaptation, psychological; breast tumor; stress; epidemiology; disease predisposition; genetic predisposition; genetic screening; genetic testing; mental stress; stress, psychological; psychological model; models, psychological; breast cancer risk; uncertainty; huntington chorea; huntington disease; disease susceptibility; perceived risk; causality; medical futility; humans; human; male; female; article |
| Journal Title: | Health Psychology |
| Volume: | 16 |
| Issue: | 1 |
| ISSN: | 0278-6133 |
| Publisher: | American Psychological Association |
| Date Published: | 1997-01-01 |
| Start Page: | 8 |
| End Page: | 19 |
| Language: | English |
| PUBMED: | 9028812 |
| PROVIDER: | scopus |
| DOI: | 10.1037/0278-6133.16.1.8 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 17 March 2017 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work