Metastatic breast carcinoma to the abdomen and pelvis Journal Article


Authors: Abu-Rustum, N. R.; Aghajanian, C. A.; Venkatraman, E. S.; Feroz, F.; Barakat, R. R.
Article Title: Metastatic breast carcinoma to the abdomen and pelvis
Abstract: Objective. The role of surgical resection of metastatic breast cancer to the abdomen and pelvis is controversial. The objective of this study is to describe the characteristics, surgical management, and outcome of women with a history of breast adenocarcinoma who developed abdominal or pelvic metastases during follow-up. Methods. We retrospectively reviewed the medical records of 40 female patients with documented invasive breast cancer who were referred to the Gynecology Service between 1986 and 1995 and were found to have metachronous abdominal and/or pelvic metastases. Results. The median patient age at exploration by the Gynecology Service was 53.5 years (range 27-79 years), and the median interval from breast cancer diagnosis to exploration was 80 months (range 9-264 months). The majority of patients, 32 (80%), had a preoperative diagnosis of a new pelvic mass or suspected abdominal carcinomatosis. With a median follow-up of 14.2 months following the diagnosis of abdominal or pelvic metastasis, the median survival for all patients was 24.1 months. Patients who had no gross residual disease in the abdomen or pelvis after surgery had a median survival of 41.6 months, which did not significantly differ from those with gross residual ≤2 cm (16.1 months) or >2 cm (18.4 months) (P = 0.624). Conclusion. Metachronous abdominal and pelvic metastases from breast cancer may appear many years following initial diagnosis and are often operated on by gynecologists because of their clinical presentation. Surgical resection may be indicated in some symptomatic patients; however, the survival advantage of surgical cytoreduction remains to be determined.
Keywords: adult; cancer survival; clinical article; treatment outcome; aged; middle aged; cancer surgery; retrospective studies; follow-up studies; cancer diagnosis; pelvis; preoperative evaluation; adenocarcinoma; metastasis; breast cancer; tumor volume; breast neoplasms; abdomen; pelvis tumor; pelvic neoplasms; breast adenocarcinoma; carcinomatosis; abdominal neoplasms; abdominal cancer; humans; prognosis; human; female; priority journal; article
Journal Title: Gynecologic Oncology
Volume: 66
Issue: 1
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 1997-07-01
Start Page: 41
End Page: 44
Language: English
DOI: 10.1006/gyno.1997.4720
PUBMED: 9234919
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
Altmetric
Citation Impact
MSK Authors
  1. Venkatraman Ennapadam Seshan
    343 Seshan
  2. Richard R Barakat
    629 Barakat