Pancreaticoduodenectomy for nonperiampullary primary tumors Journal Article


Authors: Harrison, L. E.; Merchant, N.; Cohen, A. M.; Brennan, M. F.
Article Title: Pancreaticoduodenectomy for nonperiampullary primary tumors
Abstract: INTRODUCTION: This review was performed to evaluate the outcome of patients undergoing pancreaticoduodenectomy (PD) for isolated metastatic or locally advanced nonperiampullary tumors at a single institution over a 13- year period. METHODS: Between 1983 and 1996, patients undergoing PD for metastatic or locally advanced nonperiampullary malignancies were identified. Medical records were reviewed and outcome factors and survival data analyzed. RESULTS: Eighteen patients were identified. The primary tumor histopathology included colon (n = 7), gastric (n = 4), renal cell (n = 3), lung (n = 2), bladder (n = 1), and melanoma (n = 1). The median length of hospital stay was 15 days (6 to 48) with one perioperative death (5.5%). The median tumor size was 5.5 cm (0.8 to 11.5), and 7 patients had positive peripancreatic lymph nodes. The median survival was 40 months, with a 5-year survival of 35%. CONCLUSIONS: Pancreaticoduodenectomy for nonperiampullary malignancy is infrequently indicated. However, in the absence of widely metastatic disease, PD should be considered for locally advanced tumors or isolated metastatic malignancy.
Keywords: adult; cancer survival; clinical article; treatment outcome; aged; middle aged; survival rate; pancreatic neoplasms; pancreaticoduodenectomy; pancreas; metastasis; tumor volume; lung neoplasms; colonic neoplasms; kidney neoplasms; length of stay; carcinoma, renal cell; colon cancer; malignant neoplastic disease; duodenum; stomach neoplasms; duodenal neoplasms; humans; human; male; female; priority journal; article
Journal Title: American Journal of Surgery
Volume: 174
Issue: 4
ISSN: 0002-9610
Publisher: Elsevier Inc.  
Date Published: 1997-10-01
Start Page: 393
End Page: 395
Language: English
DOI: 10.1016/s0002-9610(97)00121-9
PUBMED: 9337160
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Murray F Brennan
    1059 Brennan
  2. Alfred M Cohen
    244 Cohen