Laparoscopic evaluation in pancreatic cancer Journal Article


Authors: Merchant, N. B.; Conlon, K. C.
Article Title: Laparoscopic evaluation in pancreatic cancer
Abstract: Pancreatic cancer continues to carry a poor overall prognosis. The majority of patients have advanced disease at the time of presentation. Dynamic, contrast-enhanced computed tomography (CT) has become the radiographic study of choice in the pre-operative staging of patients with pancreatic cancer. While it has been shown to be highly sensitive in determining unresectability of peri-ampullary tumors, the ability of CT to predict accurately which tumors can be safely resected is still limited. Laparoscopic staging of peri-ampullary tumors is superior to dynamic CT in visualizing small liver and peritoneal metastases. The addition of laparoscopic ultrasound during laparoscopic staging enhances the ability of laparoscopy to determine resectability of these tumors and approaches the accuracy of open exploration without increasing significant morbidity or mortality. Patients who are deemed unresectable at the time of laparoscopy can undergo palliative biliary and/or gastric bypass procedures laparoscopically and further minimize the morbidity of laparotomy.
Keywords: treatment outcome; review; pancreas cancer; pancreatic neoplasms; cancer staging; magnetic resonance imaging; neoplasm staging; laparoscopy; preoperative evaluation; sensitivity and specificity; cancer palliative therapy; adenocarcinoma; palliative care; quality of life; computer assisted tomography; algorithms; biopsy; liver metastasis; contrast enhancement; peritoneum metastasis; biliary tract surgical procedures; cost-benefit analysis; angiography; ultrasonography; drainage; endosonography; cholestasis; stents; endoscopic retrograde cholangiopancreatography; vater papilla carcinoma; jejunostomy; extrahepatic bile duct obstruction; stomach bypass; gastric bypass; humans; human; priority journal; biliopancreatic diversion; surgical anastomosis; x-ray computed tomography; cholecystostomy; laparoscopic surgical procedures; stomach/surgery
Journal Title: Seminars in Surgical Oncology
Volume: 15
Issue: 3
ISSN: 8756-0437
Publisher: John Wiley & Sons  
Date Published: 1998-10-01
Start Page: 155
End Page: 165
Language: English
DOI: 10.1002/(sici)1098-2388(199810/11)15:3<155::aid-ssu4>3.0.co;2-a
PUBMED: 9779627
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 12 December 2016 -- Source: Scopus
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  1. Kevin C Conlon
    120 Conlon