Preoperative radiation therapy followed by low anterior resection with coloanal anastomosis Journal Article
| Author: | Minsky, B. D. |
| Article Title: | Preoperative radiation therapy followed by low anterior resection with coloanal anastomosis |
| Abstract: | The advantage of preoperative therapy in patients with clinically resectable transmural rectal cancer is to increase sphincter preservation while obtaining a high likelihood of local control. In patients who undergo a prospective clinical assessment and are declared to require an abdominoperineal resection, preoperative radiation therapy, either alone or when combined with chemotherapy, allows approximately 80% of patients to undergo a low anterior resection with or without coloanal anastomosis. The majority have good-to-excellent sphincter function. This conservative approach may be an alternative to an abdominoperineal resection in selected patients. |
| Keywords: | human tissue; human cell; review; cancer localization; patient selection; adjuvant therapy; cancer radiotherapy; preoperative care; chemotherapy, adjuvant; radiotherapy, adjuvant; methodology; prospective study; prospective studies; surgical approach; prediction; physiology; abdomen; adjuvant chemotherapy; remission; remission induction; forecasting; cancer control; rectum carcinoma; anastomosis; rectal neoplasms; rectum tumor; surgical anatomy; colon; anastomosis, surgical; perineum; anal canal; humans; human; priority journal |
| Journal Title: | Seminars in Radiation Oncology |
| Volume: | 8 |
| Issue: | 1 |
| ISSN: | 1053-4296 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1998-01-01 |
| Start Page: | 30 |
| End Page: | 35 |
| Language: | English |
| DOI: | 10.1016/s1053-4296(98)80034-9 |
| PUBMED: | 9516581 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 12 December 2016 -- Source: Scopus |
