Emerging role of laparoscopy in the diagnosis of lymphoma Journal Article


Authors: Mann, G. B.; Conlon, K. C.; LaQuaglia, M.; Dougherty, E.; Moskowitz, C. H.; Zelenetz, A. D.
Article Title: Emerging role of laparoscopy in the diagnosis of lymphoma
Abstract: Purpose: The results of laparoscopic procedures on patients with suspected or known lymphoma were analyzed to review the application and define the role of laparoscopy in lymphoma. Patients and Methods: The hospital records of 94 patients who underwent 101 procedures between June 1993 and October 1996 were reviewed for demographic and clinicopathologic information. Results: The procedure was diagnostic in 85 patients, either at primary presentation (48 patients), possible relapse (21 patients), in the course of treatment (eight patients), or of a liver lesion (eight patients). In the remaining 16 patients, it was used to stage possible intraabdominal disease. Twenty-seven patients had a previous unsuccessful diagnostic procedure. There were no operative deaths and eight postoperative complications (8%). The laparoscopy revealed non-Hodgkin's lymphoma (NHL) in 48 patients, Hodgkin's disease (HD) in 14 patients, other neoplastic conditions in six patients, and benign conditions in 33 patients. There was adequate information in all procedures in which lymphoma was diagnosed for treatment decisions. There was one false-negative and one nonresult for technical reasons. Ten patients commenced chemotherapy before discharge after a median delay of 3.5 days. In five of 24 patients (21%) with recurrent or persistent lymphoma, the precise diagnosis was significantly different from the original one. Conclusion: From our experience, laparoscopy can safely provide tissue samples of suspected lymphoma for full diagnostic analysis. It should be considered when percutaneous biopsy is not technically possible, when chromosomal or genetic analysis is needed for treatment decisions, or when the results of percutaneous biopsy are inadequate to make therapeutic decisions.
Keywords: adolescent; adult; cancer chemotherapy; child; aged; aged, 80 and over; middle aged; major clinical study; histopathology; cancer staging; lymph nodes; laparoscopy; diagnostic accuracy; relapse; retrospective study; biopsy; hodgkin disease; postoperative complication; liver; nonhodgkin lymphoma; lymphoma; abdominal neoplasms; humans; human; male; female; priority journal; article
Journal Title: Journal of Clinical Oncology
Volume: 16
Issue: 5
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 1998-05-01
Start Page: 1909
End Page: 1915
Language: English
PUBMED: 9586909
PROVIDER: scopus
DOI: 10.1200/JCO.1998.16.5.1909
DOI/URL:
Notes: Article -- Export Date: 12 December 2016 -- Source: Scopus
Altmetric Score
MSK Authors
  1. Craig Moskowitz
    373 Moskowitz
  2. Kevin C Conlon
    112 Conlon
  3. Andrew D Zelenetz
    551 Zelenetz