Ultrasonic surgical aspiration for vaginal intraepithelial neoplasia Journal Article


Authors: Matsuo, K.; Chi, D. S.; Walker, L. D.; Rosenshein, N. B.; Im, D. D.
Article Title: Ultrasonic surgical aspiration for vaginal intraepithelial neoplasia
Abstract: Objective: To determine the safety and efficacy of ultrasonic surgical aspiration (USA) in the treatment of vaginal intraepithelial neoplasia (VAIN). Methods: Using the ICD code for VAIN, all patients who underwent USA were evaluated. Patient demographics, clinicopathologic data, and follow-up outcomes were abstracted from the medical records. Results: Ninety-two patients underwent USA for VAIN. No surgical complications or postoperative scarring were recorded, and all patients were followed without further therapy after the procedure. Pathologic evaluation of the degree of VAIN in the aspirate obtained at the time of USA correlated with the preoperative biopsy results in all cases. With a median follow-up period of 4.5 years, the overall recurrence rate was 19.6%. The recurrence rate for high grade VAIN was significantly greater than that for low grade VAIN (32.3% vs 13.1%, P = 0.044). Conclusion: Ultrasonic surgical aspiration is a safe and effective surgical option for VAIN, providing a histologic sample with minimal invasiveness. © 2008 International Federation of Gynecology and Obstetrics.
Keywords: adult; controlled study; treatment outcome; treatment response; middle aged; cancer surgery; retrospective studies; major clinical study; histopathology; cancer recurrence; treatment; follow-up studies; cancer grading; neoplasm recurrence, local; tumor biopsy; postoperative complications; carcinoma in situ; gynecologic surgical procedures; ultrasonic surgical aspiration; vaginal intraepithelial neoplasia; ultrasonography, interventional; vaginal neoplasms
Journal Title: International Journal of Gynecology and Obstetrics
Volume: 105
Issue: 1
ISSN: 0020-7292
Publisher: Wiley-Blackwell Publishing Ltd.  
Date Published: 2009-04-01
Start Page: 71
End Page: 73
Language: English
DOI: 10.1016/j.ijgo.2008.11.040
PUBMED: 19150056
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: IJGOA" - "Source: Scopus"
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  1. Dennis S Chi
    710 Chi