Authors: | Inoue, D.; Abdel-Wahab, O. |
Article Title: | Modeling SF3B1 mutations in cancer: Advances, challenges, and opportunities |
Abstract: | In this issue of Cancer Cell, Obeng et al. identify the consequences of expressing the most common mutation in the spliceosomal gene SF3B1 on hematopoiesis. The knockin mouse model described represents a valuable tool to dissect the effects of SF3B1 mutations on transformation, splicing, and less well-characterized functions of SF3B1. © 2016 Elsevier Inc. |
Journal Title: | Cancer Cell |
Volume: | 30 |
Issue: | 3 |
ISSN: | 1535-6108 |
Publisher: | Cell Press |
Date Published: | 2016-09-12 |
Start Page: | 371 |
End Page: | 373 |
Language: | English |
DOI: | 10.1016/j.ccell.2016.08.013 |
PROVIDER: | scopus |
PUBMED: | 27622329 |
PMCID: | PMC5569387 |
DOI/URL: | |
Notes: | Short Survey -- Export Date: 6 December 2016 -- Source: Scopus |