Designing exercise clinical trials for older adults with cancer: Recommendations from 2015 Cancer and Aging Research Group NCI U13 meeting Journal Article


Authors: Kilari, D.; Soto-Perez-de-Celis, E.; Mohile, S. G.; Alibhai, S. M. H.; Presley, C. J.; Wildes, T. M.; Klepin, H. D.; Demark-Wahnefried, W.; Jatoi, A.; Harrison, R.; Won, E.; Mustian, K. M.
Article Title: Designing exercise clinical trials for older adults with cancer: Recommendations from 2015 Cancer and Aging Research Group NCI U13 meeting
Abstract: Cancer and its treatment can lead to a myriad of adverse events and negatively impact quality of life of older cancer patients and survivors. Unmet physical activity needs vary across the cancer continuum and remain an important yet understudied area of research in this population. Exercise interventions have been shown to be effective in treating both the physical and psychological declines associated with cancer and its treatment, with a potential to improve cancer-related outcomes. Despite the current evidence, exercise is clearly underutilized due to several barriers and knowledge gaps in existing trials that include appropriate population identification, design, and outcome measures selection. The benefits of regular exercise in both the primary and secondary prevention of chronic conditions are well established in the non-cancer population. In older cancer patients and survivors, further research is needed before exercise gains widespread acceptance. The Cancer and Aging Research Group convened experts in exercise, aging and cancer to evaluate current scientific evidence and knowledge gaps in geriatric exercise oncology. This report summarizes these findings and provides future research directions. © 2016
Keywords: exercise; older patients; cancer; geriatric recommendations
Journal Title: Journal of Geriatric Oncology
Volume: 7
Issue: 4
ISSN: 1879-4068
Publisher: Elsevier Inc.  
Date Published: 2016-07-01
Start Page: 293
End Page: 304
Language: English
DOI: 10.1016/j.jgo.2016.04.007
PROVIDER: scopus
PMCID: PMC4969104
PUBMED: 27197916
DOI/URL:
Notes: Review -- Export Date: 1 November 2016 -- Source: Scopus
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  1. Elizabeth Siryeon Won
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