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Solution structure of a quinomycin bisintercalator-DNA complex

Journal Article

Chen, H.; Patel, D. J.
Journal of Molecular Biology (1995)

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Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: Intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C(8)-modified syn guanine and adjacent unpaired 3'-adenine into the major groove

Journal Article

Mao, B.; Hingerty, B. E.; Broyde, S.; Patel, D. J.
Biochemistry (1995)

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Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: Intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer

Journal Article

Cosman, M.; Laryea, A.; Fiala, R.; Hingerty, B. E.; Amin, S.; Geacintov, N. E.; Broyde, S.; Patel, D. J.
Biochemistry (1995)

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Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: Intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove

Journal Article

Cosman, M.; Fiala, R.; Hingerty, B. E.; Amin, S.; Geacintov, N. E.; Broyde, S.; Patel, D. J.
Biochemistry (1994)

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Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: Intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove

Journal Article

Cosman, M.; Fiala, R.; Hingerty, B. E.; Amin, S.; Geacintov, N. E.; Broyde, S.; Patel, D. J.
Biochemistry (1994)

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Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: Intercalation of the covalently attached benzo[c]phenanthrene to the 5′-side of the adduct site without disruption of the modified base pair

Journal Article

Cosman, M.; Fiala, R.; Hingerty, B. E.; Laryea, A.; Lee, H.; Harvey, R. G.; Amin, S.; Geacintov, N. E.; Broyde, S.; Patel, D.
Biochemistry (1993)

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Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: Intercalation of the covalently attached benzo[α]pyrenyl ring into the helix and displacement of the modified deoxyguanosine

Journal Article

Cosman, M.; de los Santos, C.; Fiala, R.; Hingerty, B. E.; Ibanez, V.; Luna, E.; Harvey, R.; Geacintov, N. E.; Broyde, S.; Patel, D. J.
Biochemistry (1993)

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Intercalating agents with covalent bond forming capability. A novel type of potential anticancer agents. 2. Derivatives of chrysophanol and emodin