Synapse - American Society of Hematology

Results (316)

Defining 2 biologically and clinically distinct groups in acute leukemia with a mixed phenotype

Journal Article

Galera, P.; Dilip, D.; Derkach, A.; Chan, A.; Zhang, Y.; Persaud, S.; Mishra, T.; Kramer, K.; Kathpalia, M.; Liu, Y.; more...
Blood (2025)

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A multi-site break through cancer trial: Phase II study investigating dual inhibition of BCL2 and menin in AML MRD using the combination of venetoclax and revumenib (trial in progress)

Meeting Abstract

Issa, G. C.; Ambinder, A. J.; Xiao, W.; Manalis, S.; Shalek, A. K.; Gondek, L. P.; Kentsis, A.; Short, N. J.; Daver, N.; Ning, J.; more...
Blood (2024)

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Demographics, characteristics, survival and outcomes in older, untreated, acute myeloid leukemia patients with NPM1 mutations or KMT2A rearrangements from the Beat AML Master Clinical Trial

Meeting Abstract

Borate, U.; Li Welkie, R.; Huang, Y.; Swords, R. T.; Traer, E.; Stein, E. M.; Lin, T. L.; Madanat, Y. F.; Patel, P. A.; Collins, R. H.; more...
Blood (2024)

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TMPRSS6 antisense oligonucleotide therapy reverses inflammation in Jak2(V617F) mutant mice

Meeting Abstract

Levy, M.; Li, H.; Dunbar, A.; Huang, Z.; Park, Y.; Lu, M.; Phattalung, P. N.; Planoutene, M.; Casu, C.; Rivella, S.; more...
Blood (2024)

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A phase 1, open-label, dose escalation and dose expansion, multicenter clinical trial to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of lomonitinib (ZE46-0134) in adults with FLT3-mutated relapsed or refractory acute myeloid leukemia

Meeting Abstract

Lin, T. L.; Koenig, K. L.; Swords, R. T.; Stein, E. M.; Baer, M. R.; Stock, W.; Madanat, Y. F.; Olin, R.; Blum, W.; Schiller, G. J.; more...
Blood (2024)

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A randomized phase 2 trial of 28-day (Arm A) versus 14-day (Arm B) schedule of venetoclax + azacitidine in newly diagnosed acute myeloid leukemia patients ≥ 60 years

Meeting Abstract

Borate, U.; Huang, Y.; Zeidner, J. F.; Swords, R. T.; Koenig, K. L.; Stein, E. M.; Baer, M. R.; Stock, W.; Madanat, Y. F.; Olin, R.; more...
Blood (2024)

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Combined human and in vivo analyses implicate the critical importance of acute myeloid leukemia associated CD8 T cells and identifies their molecular dysfunction

Meeting Abstract

Chu, Y. E.; Cottam, M. A.; Potts, C. R.; Dickerson, K. M.; Jenkins, M. T.; Cartailler, J. A.; Lu, R.; Lee, S. C.; Levine, R. L.; Bowman, R. L.; more...
Blood (2024)

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Outcomes and survival in newly diagnosed, older, acute myeloid leukemia patients from the beat AML master trial in the venetoclax/azacitidine age

Meeting Abstract

Borate, U.; Huang, Y.; Li Welkie, R.; Swords, R. T.; Traer, E.; Stein, E. M.; Lin, T. L.; Madanat, Y. F.; Patel, P. A.; Collins, R. H.; more...
Blood (2024)

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IDH2 mutation is associated with favorable outcome among older adults with newly diagnosed acute myeloid leukemia treated with lower-intensity therapy