Research Focus

Former Employee. Chemical Biology Program; Research Fellow

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1. Nontranscriptional role of hif-1α in activation of γ-secretase and notch signaling in breast cancer

   Journal Article

   Villa, J. C.; Chiu, D.; Brandes, A. H.; Escorcia, F. E.; Villa, C. H.; Maguire, W. F.; Hu, C. J.; de Stanchina, E.; Simon, M. C.; Sisodia, S. S.; more...
   Cell Reports (2014)

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2. Familial Alzheimer disease presenilin-1 mutations alter the active site conformation of γ-secretase

   Journal Article

   Chau, D. M.; Crump, C. J.; Villa, J. C.; Scheinberg, D. A.; Li, Y. M.
   Journal of Biological Chemistry (2012)

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3. Regulation of gamma-secretase in breast cancer cells

   Meeting Abstract

   Li, Y. M.; Chien, J.
   Cancer Research (2011)

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