Synapse - Hong-Fen Guo

Results (51)

Pretargeted alpha radioimmunotherapy (DOTA-PRIT) for HER2-expressing human gastric cancer: A theranostic approach using 111(In)/225(Ac)-radiohapten

Meeting Abstract

Cheal, S.; McDevitt, M.; Burnes Vargas, D.; Veach, D.; Punzalan, B.; Xu, H.; Guo, H. F.; Ouerfelli, O.; Cheung, N. K.; Larson, S.
Journal of Nuclear Medicine (2020)

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(225)Ac-alpha pretargeted radioimmunotherapy (DOTA-PRIT) of human colorectal cancer: Achieving 100% complete responses with single-cycle targeting of 2 distinct antigens, HER2 and GPA33

Meeting Abstract

Cheal, S.; McDevitt, M.; Burnes Vargas, D.; Veach, D.; Punzalan, B.; Xu, H.; Guo, H. F.; Ouerfelli, O.; Larson, S.; Cheung, N. K.
Journal of Nuclear Medicine (2020)

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Alpha radioimmunotherapy using (225)Ac-proteus-DOTA for solid tumors – Safety at curative doses

Journal Article

Cheal, S. M.; McDevitt, M. R.; Santich, B. H.; Patel, M.; Yang, G.; Fung, E. K.; Veach, D. R.; Bell, M.; Ahad, A.; Burnes Vargas, D.; more...
Theranostics (2020)

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Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies

Journal Article

Santich, B. H.; Park, J. A.; Tran, H.; Guo, H. F.; Huse, M.; Cheung, N. K. V.
Science Translational Medicine (2020)

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An N-acetylgalactosamino dendron-clearing agent for high-therapeutic-index DOTA-hapten pretargeted radioimmunotherapy

Journal Article

Cheal, S. M.; Patel, M.; Yang, G.; Veach, D.; Xu, H.; Guo, H. F.; Zanzonico, P. B.; Axworthy, D. B.; Cheung, N. K. V.; Ouerfelli, O.; more...
Bioconjugate Chemistry (2020)

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PD-L1 checkpoint blockade augments anti-tumor immune response of GD2 or HER2-BsAb ex vivo armed T-cells (EVAT) therapy in osteosarcoma

Meeting Abstract

Park, J. A.; Guo, H. F.; Xu, H.; Cheung, N. K. V.
Blood (2019)

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Novel T-cell engaging antibodies against L1CAM for neuroblastoma

Meeting Abstract

Suzuki, M.; Xu, H.; Guo, H.; Nemieboka, B.; Wu, Z.; Lewis, J.; Cheung, N. K. V.
Cancer Research (2018)

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Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma

Journal Article

Cheal, S. M.; Xu, H.; Guo, H. F.; Patel, M.; Punzalan, B.; Fung, E. K.; Lee, S. G.; Bell, M.; Singh, M.; Jungbluth, A. A.; more...
Theranostics (2018)

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Potent anti-tumor effect using T cells armed with recombinant anti-GD2 bispecific antibodies against GD2 positive tumor

Meeting Abstract

Nakajima, M.; Guo, H.; Hoseini, S. S.; Xu, H.; Cheung, N. K.
Pediatric Blood and Cancer (2018)

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Development of a tetravalent anti-GPA33/anti-CD3 bispecific antibody for colorectal cancers

Journal Article

Wu, Z.; Guo, H. F.; Xu, H.; Cheung, N. K. V.
Molecular Cancer Therapeutics (2018)

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