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Alison Michele Schram

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Journal Article (23)
  2. Meeting Abstract (22)
  3. Research Letter (1)
Groups
  1. Department of Medicine (46)
  2. Early Drug Development Service (46)
  3. Gynecologic Medicine Service (46)
  4. Human Oncology and Pathogenesis Program (46)
  5. Solid Tumor Oncology Division (46)
  6. GSK Faculty (45)

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People
  1. David Hyman (28)
  2. Michael Berger (23)
  3. Alexander Drilon (22)
  4. Marc Ladanyi (16)
  5. Helen Won (13)
  6. Ahmet Zehir (12)

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Years
  1. 2024 (3)
  2. 2023 (3)
  3. 2022 (5)
  4. 2021 (5)
  5. 2020 (6)
  6. 2019 (11)

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Publications
  1. Cancer Research (9)
  2. Journal of Clinical Oncology (9)
  3. Cancer Discovery (5)
  4. Clinical Cancer Research (3)
  5. Annals of Oncology (2)
  6. Blood (2)

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Publishers
  1. American Association for Cancer Research (18)
  2. American Society of Clinical Oncology (10)
  3. Nature Publishing Group (8)
  4. American Society of Hematology (2)
  5. Elsevier Inc. (2)
  6. Oxford University Press (2)

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Results (46)

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  • Capivasertib (AZD5363) in combination with fulvestrant in PTEN-mutant ER+ metastatic breast cancer
    Meeting Abstract

    Smyth, L. M.; Batist, G.; Meric-Bernstam, F.; Kabos, P.; Spanggaard, I.; Lluch, A.; Schram, A.; Varga, A.; Wong, A.; Ambrose, H.; more...
    Cancer Research (2020)

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  • Efficacy and determinants of response to HER kinase inhibition in HER2-mutant metastatic breast cancer
    Journal Article

    Smyth, L. M.; Piha-Paul, S. A.; Won, H. H.; Schram, A. M.; Saura, C.; Loi, S.; Lu, J.; Shapiro, G. I.; Juric, D.; Mayer, I. A.; more...
    Cancer Discovery (2020)

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  • Clinical proof of concept for MCLA-128, a bispecific HER2/3 antibody therapy, in NRG1 fusion-positive cancers
    Meeting Abstract

    Schram, A. M.; O'Reilly, E. M.; Somwar, R.; Benayed, R.; Shameem, S.; Chauhan, T.; Torrisi, J.; Ford, J.; Maussang, D.; Wasserman, E.; more...
    Molecular Cancer Therapeutics (2019)

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  • Real-world outcomes of an automated physician support system for genome-driven oncology
    Journal Article

    Tao, J. J.; Eubank, M. H.; Schram, A. M.; Cangemi, N.; Pamer, E.; Rosen, E. Y.; Schultz, N.; Chakravarty, D.; Philip, J.; Hechtman, J. F.; more...
    JCO Precision Oncology (2019)

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  • Generation and characterization of novel preclinical disease models of NSCLC with NRG1 rearrangements to improve therapy
    Meeting Abstract

    Gladstone, E.; Vojnic, M.; Offin, M.; Delasos, L.; Lui, A.; Siau, E.; Sato, H.; Benayed, R.; Kurth, R.; Mattar, M.; more...
    Journal of Thoracic Oncology (2019)

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  • Clinicopathologic characteristics of NRG1 fusion-positive cancers: A single-institution study
    Meeting Abstract

    Schram, A. M.; Benayed, R.; Somwar, R.; Rekhtman, N.; Arcila, M. E.; Ladanyi, M.; Hyman, D. M.; Drilon, A. E.
    Journal of Clinical Oncology (2019)

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  • Paired tumor and cfDNA in patients with HER2-mutant solid tumors treated with neratinib reveals convergence of multiple on-target resistance mechanisms: Results from the SUMMIT "Basket" Trial
    Meeting Abstract

    Won, H. H.; Selcuklu, S. D.; Piha-Paul, S. A.; Saura, C.; Rodon, J.; Mayer, I. A.; Loi, S.; Shapiro, G. I.; Lu, J.; Brufsky, A.; more...
    Cancer Research (2019)

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  • Prospective clinical sequencing distinguishes independent primary cancers from recurrent or metastatic disease
    Meeting Abstract

    Schram, A. M.; Bandlamudi, C.; Zehir, A.; Ladanyi, M.; Berger, M. F.; Taylor, B. S.; Hyman, D. M.
    Cancer Research (2019)

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  • Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
    Meeting Abstract

    Cocco, E.; Kulick, A.; Misale, S.; Yaeger, R.; Razavi, P.; Won, H. H.; Ptashkin, R.; Hechtman, J. F.; Toska, E.; Cownie, J.; more...
    Cancer Research (2019)

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  • A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA
    Meeting Abstract

    Patel, J.; Hasan, M.; Meng, F.; Jing, X.; Tam, G.; Johnson, I.; Zheng, Y.; Bandlamudi, C.; Stewart, C.; Won, H.; more...
    Cancer Research (2019)

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